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Jinbao Xiang
Medicinal chemistry
Organic electrosynthesis, drug discovery and chemical biology
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Contact Information
Email    jbxiang@jlu.edu.cn
Office     Room 612, Pharmaceutical Science Building, Jilin University, Changchun, P. R. China, Tel: 0431-85619260               
Lab        Room 612, Pharmaceutical Science Building, 0431-85619260
Short Biography
Dr. Xiang was born in 1983 at Yongkang City, Zhejiang Province. He received his bachelor’s degree (2004) and Ph.D. degree (2008) from Jilin University. and then became a Lecturer in Jilin University. He was a visiting scholar in Scripps Research (USA) from 2017 to 2019. Since 2019, he is a professor in the School of Pharmaceutical Sciences, Jilin University.
Research Interest
1. Organic electrosynthesis, especially in developing highly selective C–C and C–heteroatom bond formation in medicinal chemistry.
2. Organic synthetic methodology, especially in developing efficient synthetic methods for novel privileged heterocyclic scaffolds.
3. Drug discovery and chemical biology, especially in the finding of highly selective protein kinases inhibitors.
Honors & Awards
Second Prize of Science and Technology Award of Jilin Province (2021)

1. Xiang, J.#; Shang, M.#; Kawamata, Y.; Lundberg, H.; Reisberg, S. H.; Chen, M.; Mykhailiuk, P.; Beutner, G.; Collins, M. R.; Davies, A.; Del Bel, M.; Gallego, G. M.; Spangler, J. E.; Starr, J.; Yang, S.; Blackmond, D. G.; Baran, P. S.*; Hindered Dialkyl Ether Synthesis with Electrogenerated Carbocations, Nature, 2019, 573, 398–402.
2. Shi, L.; Zheng, L.; Ning, S.; Gao, Q.; Sun, C.; Zhang, Z.; Xiang, J.*; Electrooxidative Dearomatization of Inactive Biphenyls to Cyclohexadienones, Organic Letters, 2022, 24, 5782–5786.
3. Ning, S.; Zheng, L.; Gao, Q.; Shi, L.; Liu, Y.; Zhang, Z.; Xiang, J.*; New Electrotriggers: p-Methoxycarbonylbenzyl (pMCB) as an Electroremovable Protecting Group for Carboxylic Acids, Phosphoric Acids and Alcohols, Green Chemistry, 2022, 24, 5632–5636.
4. Wang, S.-T.; Zheng, L.*; Song, S.; Wang, S.-Y.; Zhang, Z.; Xiang, J.*; Catalyst-Controlled Regiodivergent Synthesis of α/β-Dipeptide Derivatives via N-Allylic Alkylation of O-Alkyl Hydroxamates with MBH Carbonates, Chemistry-An Asian Journal, 2022, 17, e202101186.
5. Wang, S.-T.; Wang, S.-Y.; Song, S.; Gao, Q.; Wen, C.; Zhang, Z.; Zheng, L.*; Xiang, J.*; Modular and Stereoselective Approach to Highly Substituted Indole/Pyrrole-Fused Diazepanones, The Journal of Organic Chemistry, 2021, 86, 6458–6466.
6. Bai, Y.; Shi, L.; Zheng, L.; Ning, S.; Che, X.; Zhang, Z.; Xiang, J.*; Electroselective and Controlled Reduction of Cyclic Imides to Hydroxylactams and Lactams, Organic Letters, 2021, 23, 2298–2302.
7. Bai, Y.#; Liu, N.#; Wang, S.-T.; Wang, S.-Y.; Ning, S.; Shi, L.; Cui L.*; Zhang, Z.; Xiang, J.*; Nickel-Catalyzed Electrochemical Phosphorylation of Aryl Bromides, Organic Letters, 2019, 21, 6835–6838.
8. Xie, W.; Liu, N.; Gong, B.; Ning, S.; Che, X.; Cui, L.*; Xiang, J.*; Electrochemical Cross‐Dehydrogenative Coupling of N‐Aryl‐tetrahydroisoquinolines with Phosphites and Indole, European Journal of Organic Chemistry, 2019, 2498–2501.
9. Xiang, J.; Zhang, Z.; Fu, R.; Ternansky, R. J.; Gladstone, P. L.; Allan, A. L.; Donate, F.; Parry, G.; Juarez, J.; Mazar, A. P.; Bai, X.*; The Discovery of Kinase Inhibitors by a Combination of Diversity-Oriented Synthesis and Selective Screening, MedChemCommun, 2016, 7, 1946−1951.
10. Xiang, J.; Zhang, Z.; Mu, Y.; Xu, X.; Guo, S.; Liu, Y.; Russo, D. P.; Zhu, H.; Yan, B.*; Bai, X.*; Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach, ACS Combinatorial Science, 2016, 18, 230–235.

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