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Faculty
Xiaoxia Han
Title
Professor
Division
Analytical Chemistry
Specialties
Raman spectroscopy of proteins
Website
https://teachers.jlu.edu.cn/XiaoxiaHan/en/
Contact Information
Email    hanxiaoxia@jlu.edu.cn
Office     Room A305, State Key Laboratory of Supramolecular Structure and Materials, Jilin University               
Lab        Room B201/B210/B612, State Key Laboratory of Supramolecular Structure and Materials, Jilin University
Short Biography
Dr. Xiaoxia Han obtained a bachelor degree in bioscience from Changchun Normal University in 2003, and got a doctoral degree in physical chemistry from Jilin University in 2009. As a postdoctoral fellow of the Japanese Society for Promotion of Science, she spent two years at chemistry department of Kwansei Gakuin University, Japan. In 2011, she, as a postdoctoral research fellow of the Alexander von Humboldt Foundation, worked at Max-Volmer-Laboratory for Biophysical Chemistry, Technical University of Berlin, Germany. In 2014, she started to work at State Key Laboratory of Supramolecular Structure and Materials, Jilin University.
Research Interest
Raman spectroscopy/surface-enhanced Raman scattering and their applications in exploration of molecular mechanisms of cell death.
Honors & Awards
1. Excellent doctoral dissertation of Jilin Province and nominated as one of The National 100 Excellent Doctoral Dissertation, 2011.
2. Postdoctoral fellowship of the Alexander von Humboldt Foundation, 2011.
3. Postdoctoral fellowship of the Japanese Society for Promotion of Science, 2009.
Publications

1. J. Tang, J. Zhu, H. Xie, L. Song, G. Xu, W. Li, L. Cai, X. X. Han*, Mitochondria-Specific Molecular Crosstalk between Ferroptosis and Apoptosis Revealed by In Situ Raman Spectroscopy. Nano Lett. 2024, 24, 2384-2391.
2. J. Zhu, J. Zhu, H. Xie, J. Tang, Y. Miao, L. Cai, P. Hildebrandt*, X. X. Han*, In Situ Raman Spectroscopy Reveals Cytochrome c Redox-Controlled Modulation of Mitochondrial Membrane Permeabilization That Triggers Apoptosis. Nano Lett. 2024, 24, 370-377.
3. J. Tang, L. Song, H. Xie, J. Zhu, W. Li, G. Xu, L. Cai, X. X. Han*, In Situ and Real-Time Monitoring of Mitochondria–Endoplasmic Reticulum Crosstalk in Apoptosis via Surface-Enhanced Resonance Raman Spectroscopy. Nano Lett. 2023, 23, 8363-8369.
4. X. X. Han*, R. S. Rodriguez, C. L. Haynes*, Y. Ozaki* and B. Zhao*, Surface-enhanced Raman spectroscopy, Nat. Rev. Methods Primers, 2021, 1, 87.
5. J. Zhu, M. Jiang, H. Ma, H. Zhang, W. Cheng, J. Li, L. Cai, X. X. Han*, B. Zhao, Redox-State-Mediated Regulation of Cytochrome c Release in Apoptosis Revealed by Surface-Enhanced Raman Scattering on Nickel Substrates. Angew. Chem. Int. Ed. 2019, 58, 16499 –16503.

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