报告题目：Pillararenes: Easy-to-Make and Versatile Receptors for Supramolecular Chemistry
Graduate School of Natural Science and Technology, Kanazawa University, Japan
Macrocyclic compounds play a major role in supramolecular chemistry because of their beautiful shape, nano-scale size and molecular recognition ability. Numerous supramolecular architectures have been constructed and studied as new components of materials as well as entities related to biological structural formation and functions using various macrocyclic hosts such as cyclodextrins, crown ethers, calixarenes and cucurbiturils.
In 2008, we reported a new class of macrocyclic hosts named “pillararenes” (Figure 1).1,2 Pillararenes have repeating units connected by methylene bridges at the para-position, and thus they have a unique symmetrical pillar architecture differing from the basket-shaped structure of meta-bridged calixarenes. Synthesis of pillararenes is easy-to-make. They can be synthesized in high yield by reacting commercially available reagents. The reaction was completed in 3 minutes. Pillararenes also show versatile functionality similar to cyclodextrins. Based on the various synthetic approaches, position-selective mono-, di-, tetra-, penta- and per-functionalization of pillararenes can be achieved. Pillararenes can capture electron accepting guest molecules within their cavity similarly to cucurbiturils. Because of their unique pillar-shaped architectures, high yield synthesis, outstanding host–guest properties, planar chirality and functionality, pillararenes are useful platform to construct various supramolecules including rotaxanes, catenanes, supramolecular polymers and sensors.
2000 B.S. Faculty of Engineering, Kyoto University, Japan.
2002 M.S. Graduate School of Engineering, Kyoto University (supervisor: Prof. Yoshiki Chujo).
2005 Ph.D, in Polymer Chemistry, Department of Polymer Chemistry, Graduate School of Engineering,
Kyoto University (supervisor: Prof. Yoshiki Chujo).
2002 JSPS Research Fellow (DC1): Department of Polymer Chemistry, Graduate School of Engineering,
2005 JSPS Research Fellow (PD): Department of Polymer Science, Graduate School of Science,
Osaka University, Japan. (Advisor: Prof. Akira Harada)
2006 Assistant Professor at Kanazawa University
2010 Associate Professor at Kanazawa University
2013 JST-PRESTO Researcher : PRESTO program
" Hyper-nano-space Design toward Innovative Functionality"
-Synthesis of Novel Macrocyclic Hosts Pillar[n]arenes
-Construction of Supramolecular Materials
2010: Award for Encouragement of Research in Polymer Science; The Society of Polymer Science, Japan
2011: HGCS Japan Award Excellence 2010
2012: The Chemical Society of Japan Award for Young Chemists
2013: 2013 Cram Lehn Pedersen Prize in Supramolecular Chemistry;
International Symposium on Macrocyclic and Supramolecular Chemistry; Royal Society of Chemistry
2014: The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science
1.“Pillar- and pillararene-based supramolecular assemblies built by using their cavity-size-depending host-guest interactions” Ogoshi. T; Yamagishi, T. Chem. Commun. 2014, DOI: 10.1039/C4CC00738G. (Feature Article)
2.“Solvent- and achiral-guest-triggered chiral inversion in a planar chiral pseudocatenane” Ogoshi, T.; Akutsu, T.; Yamafuji, D.; Aoki, T.; Yamagishi. T. Angew. Chem. Int. Ed. 2013, 52, 8111-8115.
3.“Solvent- and achiral-guest-triggered chiral inversion in a planar chiral pseudocatenane” Ogoshi, T.; Shiga, R.; Yamagishi. T. J. Am. Chem. Soc. 2012, 134, 4577-4580.