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李菲
职  称:
教授
专  业:
物理化学
研究方向:
核磁共振波谱学  结构生物学
主  页:
Home URL
联系方式
邮 箱:
feili@jlu.edu.cn
办公室:
吉林大学无机超分子楼A303室 0431-85168548
实验室:
吉林大学无机超分子楼
个人简历
分别于1982、1985和2000年获吉林大学理学学士、理学硕士和理学博士学位,1985年起在吉林大学理论化学研究所/超分子结构与材料国家重点实验室工作,1985-1987年任助教,1987-1992年任讲师,1992-2001年任副教授,2001年起至今任教授。
研究兴趣
用谱学方法和生物物理学方法研究膜蛋白在膜模拟环境中的结构;膜蛋白与磷脂膜及底物的相互作用;淀粉样多肽的聚集和其纤维化的抑制
代表性论文
1. Yunrui Wang, Lingling Wang, Fei Li*, Micelle-bound structure of an extracellular Met-rich domain of hCtr1 and its binding with silver. RSC Adv., 2013, 3, 15245-15253.
2. Lei Yang, Zhaowei Huang, Fei Li*, Structural insights into the transmembrane domains of human copper transporter 1. J. Pept. Sci. 2012 (July), 18, 449-455.
3. Jiantao Li, Lingling Wang, Li Wang, Fei Li*, Structure and transmembrane topology of Slc11a1 TMD1-5 in lipid membranes. Biopolymers (Pept. Sci.) 2012, 98, 224-233.
4. Shuyan Xiao, Lei Yang, Fei Li*, The structure and assembly model of the third transmembrane domain of Slc11a1 in SDS micelles revealed by NMR study of the leucine-substituted peptide. J. Pept. Sci. 2012, 18, 45-51.
5. Dan Wang, Yuande Song, Jiantao Li, Chunyu Wang, Fei Li*, Structure and metal ion binding of the first transmembrane domain of DMT1. Biochim. Biophys. Acta (Biomembranes) 2011, 1808, 1639-1644.
6. Shuo Wang, Jiayi Yu, Wei Li, Fei Li*, Structural study of an active analog of EX-4 in solution and micelle associated states. Biopolymers (Pept. Sci.) 2011, 96, 348-357.
7. Shuyan Xiao, Jiantao Li, Yuxia Wang, Chunyu Wang, Rong Xue, Shuo Wang, Fei Li*, Identification of an "-helix-extended segment--helix" conformation of the sixth transmembrane domain in DMT1. Biochim. Biophys. Acta (Biomembranes) 2010, 1798, 1556-1564.
8. Rong Xue, Shuo Wang, Haiyan Qi, Yuande Song, Shuyan Xiao, Chunyu Wang; Fei Li*, Structure and topology of Slc11a1(164-191) with G169D mutation in membrane-mimetic environments. J. Struct. Biol. 2009, 165, 27-36.
9. Yuande Song, Dan Wang, Haiyan Qi, Shuyan Xiao, Rong Xue, Fei Li*, Metal ion binding of the first external loop of DCT1 in aqueous solution. Metallomics 2009, 1, 392-394.
10. Rong Xue, Shuo Wang, Haiyan Qi, Yuande Song, Chunyu Wang, Fei Li*, Structure analysis of the fourth transmembrane domain of Nramp1 in model membranes. Biochim. Biophys. Acta (Biomembranes) 2008, 1778, 1444-1452.